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Implanon does not contain estrogen.The Implanon implant must be removed after 3 years. The exact location of the implant in the arm should be verified by palpation.

Implanon is inserted through a needle (under local anesthesia) into the skin of your upper arm, just inside and above the elbow. To reduce the risk of neural or vascular injury, the implant should be inserted at the inner side of the non-dominant upper arm about 8-10 cm (3-4 inches) above the medial epicondyle of the humerus. Each conception was likely to have occurred shortly before or within 2 weeks after Implanon removal. It is not known if Implanon is as effective in very overweight women because studies did not include many overweight women.The following chart shows the chance of getting pregnant for women who use different methods of birth control. It is therefore possible that Implanon may be less effective in overweight women, especially in the presence of other factors that decrease serum etonogestrel concentrations such as concomitant use of hepatic enzyme inducers.Overdosage may result if more than 1 implant is inserted. Consequently, plasma concentrations may either increase (for example, cyclosporine) or decrease (for example, lamotrigine). On rare occasion, surgery may be required.Women who currently have or have had breast cancer should not use hormonal contraception because breast cancer may be hormonally sensitive Some studies suggest that the use of combination hormonal contraceptives is associated with an increase in the risk of cervical cancer or intraepithelial neoplasia. The rod can remain in place and provide continuous contraception for up to 3 years.Implanon may also be used for purposes not listed in this medication guide.You should not use an Implanon if you have any of the following conditions: unusual vaginal bleeding, liver disease or liver cancer, or if you have ever had breast or uterine cancer, a heart attack, a stroke, or a blood clot.Using an Implanon implant can increase your risk of blood clots, stroke, or heart attack, especially if you have certain other conditions, or if you are overweight.Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Protect from light. We comply with the HONcode standard for trustworthy health information - If the infection persists, the implant should be removed. The applicator is for single use only and should be disposed in accordance with the Center for Disease Control and Prevention guidelines for handling of hazardous waste.Once the non-palpable implant has been located, removal is recommended Before initiating the removal procedure, the healthcare provider should carefully read the instructions for removal and consult the USER CARD and/or the PATIENT CHART LABEL for the location of the implant. Call your doctor for medical advice about side effects. Expulsion or migration of the implant has been reported, including to the chest wall. Start using another form of birth control right away if you wish to avoid an unintended pregnancy.Using Implanon can increase your risk of blood clots, stroke, or heart attack. For details on etonogestrel blood level determination, call 1-877-Implanon (1-877-467-5266) for further instructions.If the implant migrates within the arm, removal may require a minor surgical procedure with a larger incision or a surgical procedure in an operating room. I should be able to feel the small rod.Most women have changes in their menstrual bleeding while using Implanon. Interactions between HCs and other drugs may lead to breakthrough bleeding and/or contraceptive failure. When possible, advise the nursing mother about both hormonal and non-hormonal contraceptive options, as steroids may not be the initial choice for these patients. Do not simultaneously retract the obturator and cannula from the patient's arm.Always verify the presence of the implant in the woman's arm immediately after insertion by palpationIf you cannot feel the implant or are in doubt of its presence, the implant may not have been inserted or it may have been inserted deeply:Until the presence of the implant has been verified, the woman should be advised to use a non-hormonal contraceptive method, such as condoms.Procedure for Removal of an Implant that is PalpableDosage and Administration (2.3), Procedure for Removal of an Implant that is Palpable,Exploratory surgery without knowledge of the exact location of the implant is strongly discouraged.The following information is based on experience with either Implanon, other progestin-only contraceptives, or experience with combination (estrogen plus progestin) oral contraceptives.General disorders and administration site conditions:Substances decreasing the plasma concentrations of hormonal contraceptives (HCs) and potentially diminishing the efficacy of HCs:Substances increasing the plasma concentrations of HCs:Human Immunodeficiency Virus (HIV)/Hepatitis C Virus (HCV) protease inhibitors and non-nucleoside reverse transcriptase inhibitors:Figure 24 Mean Serum Concentration-time Profile of Etonogestrel During 2 Years of Implanon Use and After Removal in 20 Healthy Womendoes not protect against HIV infection (the virus that causes AIDS) or other sexually transmitted diseases.What if I need birth control for more than 3 years?Immediately after the Implanon implant has been placed, you and your healthcare provider should check that the implant is in your arm by feeling for it.If at any time you cannot feel the Implanon implant, contact your healthcare provider immediately and use a non-hormonal birth control method (such as condoms) until your healthcare provider confirms that the implant is in place.What are the most common side effects I can expect while using Implanon?Changes in Menstrual Bleeding Patterns (menstrual periods)Call your healthcare provider right away if you haveAfter Implanon is inserted, I should check that it is in place by gently pressing my fingertips over the skin in my arm where Implanon was inserted.

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